M-D-Y
Initials of RA conducting screen
* must provide value
Date of initial note
* must provide value
Today M-D-Y
Thank you for your interest in our research studies. The following screening survey is set up to determine if you may qualify for one of our current studies. These questions will take between 5-10 minutes. If we determine that you may qualify, a study staff member will provide you with more detailed information about the study and will ask you some additional questions to determine if you are eligible to complete the screening session. You may also call our lab at 919-907-9955 if you prefer to talk to a staff member directly.
Answering these questions is voluntary. You are under no obligation to answer them, and not answering them will have no effect on your health care at Duke. Not answering the questions, however, means that you will not be eligible to participate in this research study. Your responses to these questions will be kept on a secure password-protected server, and only staff members associated with this study have access to the data. While we do our best to protect your information, there is always a risk of breach of confidentiality. If at any time during this prescreening you would like to stop and not participate you may simply close your browser.
Below is a description of our current study. Please take a minute to read the description.
The purpose of this study is to evaluate how certain childhood experiences influences brain function and responses to nicotine exposure in a group of nonsmoking young adults. We assess responses to nicotine exposure by giving participants a small amount of nicotine or placebo, and then asking them to answer questionnaires. The investigational drugs used in this study are a nicotine nasal spray (i.e., Nicotrol) and/or a nasal spray placebo (made of common kitchen ingredients, including a very tiny amount of pepper extract also called capsaicin). We assess brain function through function magnetic resonance imaging (fMRI), which is a noninvasive procedure that uses a magnetic field to take pictures of your brain while you are performing certain tasks.
We are recruiting healthy individuals between the ages of 18 and 21 who have never smoked a full cigarette or used other tobacco products (e.g., vaping, blunts, or hookah). This study requires a total of 1 remote visit and 6 in-person visits, each lasting between 2 and 4 hours, and will take 4-6 weeks to complete the entire study. You will have blood drawn to measure nicotine levels at the end of each experimental session (3 total), and you will be asked to provide urine samples to test for recent drug use and pregnancy (if necessary). You can earn up to $925 for completing all aspects of the study.
Would you like to continue with the screening questions?
* must provide value
Yes, I would like to continue with the screening.
No, I am not interested at this time.
WHEN COMPLETING PHONE SCREEN, OPEN FORM TITLED "NeuroNic PHONE SCREEN SCRIPT" AND READ TO ALL PARTICIPANTS BEFORE BEGINNING SCREEN
First Name
* must provide value
Best phone number to reach you
* must provide value
Best time to reach you during business hours?
Preferred Method of Contact:
Sex assigned at birth
* must provide value
Female
Male
Intersex/Ambiguous
Which of the following describes how you think of yourself?
* must provide value
Female or primarily feminine
Male or primarily masculine
Both male and female
Neither male nor female
In another way
What are your preferred pronouns? _____________
* must provide value
She/Her/hers
He/him/his
They/them/theirs
Other (please specify)
What is your race?
* must provide value
American Indian, Alaskan Native
Asian
Black/African American
Native Hawaiian/Pacific Islander
White
Other (specify)
Are you of Hispanic, Latino, or Spanish origin?
* must provide value
No, not of Hispanic, Latino, or Spanish origin
Yes, Mexican, Mexican Am., Chicano
Yes, Puerto Rican
Yes, Cuban
Yes, another Hispanic, Latino, or Spanish origin (specify)
Are you a student?
* must provide value
Yes, full time
Yes, part time
No
What school do you attend?
How many cigarettes have you smoked in your lifetime?
* must provide value
< 1 whole cigarette 1-5 cigarettes 6-10 cigarettes > 10 cigarettes
How many times have you used any other forms of tobacco (e.g., hookah, e-cigarettes like JUUL, blunts, cigarillos, etc.) in your lifetime?
* must provide value
< 1 time 1-5 times 6-10 times >10 times
Have you used any tobacco products, even a puff of a cigarette, in the past year?
* must provide value
Yes
No
Do you think you might use a cigarette, e-cigarette, or other tobacco product over the next month?
* must provide value
Definitely Probably Unsure Probably Not Definitely Not
Below is a list of 9 categories of Adverse Childhood Experiences (ACEs). From the list below, please consider each category and whether you experienced this prior to your 18th birthday.
-Did you feel that you didn't have enough to eat, had to wear dirty clothes, or had no one to protect or take care of you?
Â
 -Did you live with anyone who was depressed, mentally ill, or attempted suicide?
 -Did you live with anyone who had a problem with drinking or using drugs, including prescription drugs?
 -Did your parents or adults in your home ever hit, punch, beat, or threaten to harm each other?
 -Did you live with anyone who went to jail or prison?
 -Did a parent or adult in your home ever swear at you, insult you, or put you down?
 -Did a parent or adult in your home ever hit, beat, kick, or physically hurt you in any way?
 -Did you feel that no one in your family loved you or thought you were special?
 -Did you experience unwanted sexual contact (such as fondling or oral/anal/vaginal intercourse/penetration)?
Please add up the number of options you mentally said, "Yes, I've experienced that," above and select the total number.
0 1 2 3 4 or more
Please add up the number of options you mentally said, "Yes, I've experienced that," above and select the total number.
* must provide value
0 1 2 3 4 or more
Now I would like to ask you some additional questions about your mental health and medical history. I would like to remind you that answering these questions is voluntary. You are under no obligation to answer them, and not answering them will have no effect on your health care at Duke.
Have you taken any antidepressants, mood stabilizers, ADHD medications, antipsychotics, or opioid pain medications in the past 60 days? (excludes benzodiazepines)
* must provide value
Yes No
How frequently do you drink alcohol?
* must provide value
Is the above response greater than once per week?
* must provide value
Yes No
In the past month, how many times have you had 4 or more drinks within a 2-hour period?
* must provide value
Have you used marijuana or any other illicit drugs more than 10 times in your lifetime?
* must provide value
Yes
No
Have you ever sought help for or had any formal treatment for drugs or alcohol?
* must provide value
Yes
No
Do any of these medical or health issues apply to you?
Current major medical problem such as heart disease, cancer, or emphysema Heart attack in the past 90 days Brain abnormality, such as stroke, brain tumor, or seizure disorder Currently pregnant, breast feeding, or trying to become pregnant Been diagnosed with schizophrenia, schizoaffective disorder, or bipolar disorder Glaucoma or color blindness or other uncorrected vision problem
* must provide value
Yes, at least one of these applies to me
No, none of these apply to me
Unsure of whether any of these apply to me
Have you ever experienced a head trauma that caused you to lose consciousness?
* must provide value
Yes
No
Do you have any metal implants or fragments in your body (including but not limited to permanent retainer, pacemaker, braces, plates, screws)?
* must provide value
Yes
No
Are you claustrophobic (afraid of dark enclosed spaces)?
* must provide value
Yes
No
Do you have any tattoos or permanent make-up above the neck?
* must provide value
Yes
No
How tall are you?
* must provide value
4' 6" or less 4' 7" 4' 8" 4' 9" 4' 10" 4' 11" 5' 0" 5' 1" 5' 2" 5' 3" 5' 4" 5' 5" 5' 6" 5' 7" 5' 8" 5' 9" 5' 10" 5' 11" 6' 0" 6' 1" 6' 2" 6' 3" 6' 4" 6' 5" 6' 6" or more
How much do you weigh?
* must provide value
BMI**note MRI eligibility - BMI < 40, or other evidence (e.g., recent MRI scan) supporting fMRI compatibility
View equation
Do you have any routine times during which you will not be able to participate in a study?
How did you hear about this study?
* must provide value
Craigslist DukeList Flyer Friend/Referral Facebook Other online ad TV ad MyChart Researchmatch.org Other
If you do not qualify for this study, would you like to be contacted for future studies?
* must provide value
Yes
No
Is the subject web screen eligible?
Eligible = 1
Ineligible = 2
Pending = 9
Not completed = 0
View equation
Complete
Not Complete
Pending
DNQ
Is the subject eligible to enroll?
Yes
No
No, but could be contacted in the future
Has screening visit been scheduled?
Yes
No, screening cannot be scheduled
Pending
Notes about scheduling screening visit
Ineligible Reasons (check all that apply)
Number of Contact Attempts
1
2
3
Notes on Phone Screen Contact Attempts
Reasons Phone Screen Cannot be Completed
Reasons Not Eligible - Calculated
Pass=1
Fail=2
Not yet assessed/Pending =9 View equation
View equation
View equation
View equation
View equation
View equation